Clinical evidence shows the power of mNGS

The clinical evidence describing what mNGS testing is, how it works and its role in the infectious disease diagnostic workup is robust and growing. Learn more about the evidence behind mNGS infectious disease testing below.

Publications

Seven-year performance of a clinical metagenomic next-generation sequencing test for diagnosis of central nervous system infections

NATURE MEDICINE 2024

Clinical Metagenomic Sequencing for Diagnosis of Meningitis and Encephalitis.

THE NEW ENGLAND JOURNAL OF MEDICINE 2019

Actionable Diagnosis of Neuroleptospirosis by Next-Generation Sequencing.

THE NEW ENGLAND JOURNAL OF MEDICINE 2014

Rapid Pathogen Detection by Metagenomic Next-Generation Sequencing of Infected Body Fluids.

NAT MED 2021

Clinical metagenomics.

NATURE REVIEWS: GENETICS 2019

Metagenomics for neurological infections — expanding our imagination.

NATURE REVIEWS: NEUROLOGY 2020

A cloud-compatible bioinformatics pipeline for ultrarapid pathogen identification from next-generation sequencing of clinical samples.

GENOME RESEARCH 2014

Enhanced Virus Detection and Metagenomic Sequencing in Patients with Meningitis and Encephalitis.

AMERICAN SOCIETY FOR MICROBIOLOGY 2021

Integrating central nervous system metagenomics and host response for diagnosis of tuberculosis meningitis and its mimics.

NATURE COMMUNICATIONS 2022

Unbiased Metagenomic Sequencing for Pediatric Meningitis in Bangladesh Reveals Neuroinvasive Chikungunya Virus Outbreak and Other Unrealized Pathogens

AMERICAN SOCIETY FOR MICROBIOLOGY 2019

Metagenomic Next-Generation Sequencing for Diagnosis of Pediatric Meningitis and Encephalitis: A Review

JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY 2021

The Comparative Utility Of Metagenomic Next-Generation Sequencing and Universal PCR for Pathogen Detection on Cerebrospinal Fluid: A Retrospective Analysis From a Tertiary Care Center

OPEN FORUM INFECTIOUS DISEASES 2019

Severe Neuroinvasive West Nile Virus in Association With Anti-CD20 Monotherapy for Multiple Sclerosis

NEUROLOGY NEUROIMMUNOLOGY & NEUROINFLAMMATION 2023

Transmission of yellow fever vaccine virus through blood transfusion and organ transplantation in the USA in 2021: report of an investigation

THE LANCET 2023

Featured Webinar

Delve co-founder Dr. Charles Chiu discusses the impact of metagenomics on infectious disease diagnosis.

Interested in talking to a member of our Medical Affairs team?